A case of cow’s milk-induced eosinophilic enterocolitis masquerading as necrotizing enterocolitis in a preterm infant with extremely low birth weight
	    		
		   		
		   			
		   		
	    	
    	 
    	10.4168/aard.2022.10.4.215
   		
        
        	
        	
        	
        		- Author:
	        		
		        		
		        		
			        		Sun-Young LEE
			        		
			        		
			        		
			        			1
			        			
			        		
			        		
			        		
			        		
			        		;
		        		
		        		
		        		
			        		Myo-Jing KIM
			        		
			        		;
		        		
		        		
		        		
			        		Jin-A JUNG
			        		
			        		;
		        		
		        		
		        		
			        		Seo-Hee RHA
			        		
			        		;
		        		
		        		
		        		
			        		Chae-Ku JO
			        		
			        		
		        		
		        		
		        		
		        		
		        			
			        		
			        		Author Information
			        		
		        		
		        		
			        		
			        		
			        			1. Department of Pediatrics, Dong-A University, College of Medicine, Busan, Korea
			        		
		        		
	        		
        		 
        	
        	
        	
        		- Publication Type:CASE REPORT
 
        	
        	
            
            
            	- From:Allergy, Asthma & Respiratory Disease
	            		
	            		 2022;10(4):215-218
	            	
            	
 
            
            
            	- CountryRepublic of Korea
 
            
            
            	- Language:English
 
            
            
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		        	Abstract:
			       	
			       		
				        
				        	 Food allergy is a rare form of feeding intolerance in preterm infants, with symptoms similar to necrotizing enterocolitis. We report a case of clinically diagnosed cow’s milk-induced eosinophilic enterocolitis in an infant with extremely low birth weight. The patient was born at 24 weeks and 1 day gestation, weighing 610 g, had repeated episodes of gastrointestinal symptoms after feeding, and was placed on nil per os. On day 67, the eosinophil count increased suddenly (7,852.8/mL), and the formula was changed to amino acid-based (Neocate). Gradually, the eosinophil count returned to normal. Ileostomy was performed and full enteral feeding was achieved with Neocate. Intraoperatively, the intestine was nonnecrotic and viable; the biopsy report showed massive mucosal eosinophilic infiltration. The patient was diagnosed with cow’s milk-induced eosinophilic enterocolitis.