Effects of Batroxobin on Acute Cerebral Infarction: A Meta-analysis
10.3969/j.issn.1006-9771.2013.03.002
- VernacularTitle:巴曲酶治疗急性脑梗死临床疗效的Meta 分析
- Author:
Jiwei CHENG
;
Yu BAI
;
Xiaojing ZHANG
;
Yuqing HOU
;
Lijun ZHANG
;
Xuefen CHEN
- Publication Type:Journal Article
- Keywords:
acute cerebral infarction, Batroxobin, Meta-analysis, neurological function, fibrinogen
- From:
Chinese Journal of Rehabilitation Theory and Practice
2013;19(3):204-209
- CountryChina
- Language:Chinese
-
Abstract:
Objective To assess the clinical effect of Batroxobin on acute cerebral infarction. Methods Randomized controlled trials (RCTs) about Batroxobin used for acute cerebral infarction were recalled. The quality of the document were assessed with Jadad scale, and the RevMan 4.3 software was used for Meta-analysis. Results 38 RCTs were recalled. 29 trials were negatively controlled, 6 controlled with Defibrase, and 3 controlled with Urokinase. Batroxobin is more effective than negative controls on neurological function score and fibrinogen (P<0.05). There was no statistics difference between Batroxobin and Urokinase on the neurological function score (P>0.05), as well as incidence of improvement between Batroxobin and Defibrase (P>0.05). Conclusion Batroxobin can effectively improve the neurological function and reduce the fibrinogen for acute cerebral infarction.
