Influence of subclinical hypothyroidism on risk of type 2 diabetes mellitus and its related factors
10.3969/j.issn.1006-2483.2022.06.036
- VernacularTitle:亚临床甲状腺功能减退对2型糖尿病发生风险的影响
- Author:
Yong-gui LI
1
;
Xiao-luan LI
1
;
Li-xin WANG
1
Author Information
1. Department of Endocrinology , Qinghai Provincial People's Hospital , Xining , Qinghai 810007 , China
- Publication Type:Journal Article
- Keywords:
Subclinical hypothyroidism;
Type 2 diabetes mellitus;
Case control study
- From:
Journal of Public Health and Preventive Medicine
2022;33(6):152-155
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the effect of subclinical hypothyroidism on the risk of type 2 diabetes mellitus (T2DM), and to conduct multivariate analysis in order to prevent it. Methods A total of 71 T2DM patients (case group) and 78 non-diabetic patients (control group) were enrolled in the study in January 2019 - 2021 December. Collect thyroid function information and potential influence factors before diagnosis of diabetes mellitus. Potential influencing factors include gender, age, family history of common chronic diseases, complications of common chronic diseases, smoking and drinking history, BMI level, blood pressure and blood lipid level. Results Univariate analysis showed that the proportion of patients with abnormal thyroid function (subclinical hypothyroidism), female, age, abnormal blood pressure, dyslipidemia and family history of diabetes was higher in case group than in control group. Multivariate regression model indicated that female (OR=1.121), dyslipidemia (OR=1.140), thyroid dysfunction (subclinical hypothyroidism) (OR=1.423) were the final indication. And family history of diabetes (OR=1.110) is the four risk factor to increase the risk of T2DM (P<0.05). Conclusion Women with subclinical hypothyroidism and dyslipidemia, who have family history of diabetes, have higher risk of T2DM. It is worthy of clinical attention and relevant preventive measures..
