Effects of antiviral therapy on the reversal of liver fibrosis
10.3969/j.issn.1001-5256.2022.11.032
- VernacularTitle:抗病毒治疗对肝纤维化逆转的影响
- Author:
Xin LUO
1
;
Ying QU
1
;
Xiaobo CAI
1
;
Lungen LU
1
Author Information
1. Department of Gastroenterology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200080, China
- Publication Type:Reviews
- Keywords:
Liver Cirrhosis;
Antiviral Agents;
Pathologic Processes
- From:
Journal of Clinical Hepatology
2022;38(11):2596-2598
- CountryChina
- Language:Chinese
-
Abstract:
As an inevitable stage in the progression of various chronic liver diseases, liver fibrosis eventually develops into liver cirrhosis or cancer. Because viral infection is a major cause of liver fibrosis, antiviral therapy is critical in the seroconversion and reversal of liver fibrosis in viral hepatitis. This review summarizes the clinical effects and underlying molecular mechanisms of antiviral therapy in the pathological reversal of liver fibrosis, as well as the current limitations, with the goal of providing literature references for upcoming clinical and basic research.
