Clinical Effects of Chinese Medicine Fasting Therapy in Overweight/Obese Type 2 Diabetes Patients
10.13471/j.cnki.j.sun.yat-sen.univ（med.sci）.2022.0412
- VernacularTitle:中医禁食疗法对超重/肥胖2型糖尿病患者的临床疗效
- Author:
Ting-ying ZHANG
1
;
Tao-li LIU
1
;
Jian-guo HU
1
;
Li ZHANG
1
;
Zhi-yu YE
1
;
Zhi-ling LI
1
;
Hong-da CHEN
1
;
Jian QIN
1
Author Information
1. Department of Traditional Chinese Medicine， The Seventh Affiliated Hospital， Sun Yat-sen University， Shenzhen 518107， China
- Publication Type:Journal Article
- Keywords:
Chinese medicine fasting therapy;
calorie restriction;
overweight/obesity;
type 2 diabetes
- From:
Journal of Sun Yat-sen University(Medical Sciences)
2022;43(4):613-620
- CountryChina
- Language:Chinese
-
Abstract:
ObjectiveTo investigate the curative effect of Chinese medicine fasting therapy in overweight/obese type 2 diabetes patients. MethodsIn this study， overweight/obese patients with type 2 diabetes were treated with Chinese medicine fasting therapy for 1 week. The clinical efficacy of all patients was evaluated and followed up for 6 months. Glycosylated hemoglobin， fasting plasma glucose， fasting insulin， HOMA-IR， weight， BMI and other indicators were tested at the end of the fasting， 3 months and 6 months after the fasting. ResultsGlycosylated hemoglobin was significantly lower at 3 months and 6 months of follow-up than that at baseline （P<0.001）. Fasting plasma glucose was significantly lower after fasting than baseline values （P<0.001）， HOMA-IR， weight and BMI were significantly lower after fasting， at 3 months and 6 months of follow-up than that of baseline （P<0.05）. Body fat rate， waist circumference and waist-to-hip ratio significantly decreased after fasting （P<0.05）. ConclusionChinese medicine fasting therapy can significantly reduce the blood glucose level of overweight/obese type 2 diabetes patients， improving insulin resistance， and the effect will continue during the 6-month follow-up period； it can also reduce body weight， BMI， waist circumference， waist-to-hip ratio and body fat rate with safety.
