Liver Stiffness Assessment by Sound Touch Elastography versus Two-dimensional Shear Wave Elastography: a Comparative Study
- VernacularTitle:声触诊弹性成像与二维剪切波弹性成像检测肝脏硬度的比较
- Author:
Jian ZHENG
1
;
Man-li WU
2
;
Qing-juan WANG
3
;
Jin-fen WANG
2
;
Min ZHANG
3
;
Xiang PENG
3
;
Xiao-hong YAO
3
;
Rong-qin ZHENG
2
Author Information
1. Department of Ultrasound, The Third People's Hospital of Longgang, Shenzhen 518115, China; Department of Ultrasound, Longgang District People's Hospital of shenzhen, Shenzhen 518115, China
2. Department of Ultrasound, The Third Affiliated Hospital of Sun Yat-Sen University, Guangzhou 510630, China
3. Department of Ultrasound, Longgang District People's Hospital of shenzhen, Shenzhen 518115, China
- Publication Type:Journal Article
- Keywords:
sound touch elastography(STE);
two-dimensional shear wave elastography(2D-SWE);
liver stiffness;
liver cirrhosis
- From:
Journal of Sun Yat-sen University(Medical Sciences)
2020;41(4):644-648
- CountryChina
- Language:Chinese
-
Abstract:
【Objective】 To compare sound touch elastography(STE), a new technique for the measurement of liver stiffness, and two-dimensional shear wave elastography(2D-SWE), and to provide an evidence base for STE’s clinical practice. 【Methods】 The study included forty-three healthy volunteers and sixty-three patients with liver cirrhosis, in which liver stiffness was measured by means of STE and 2D-SWE. We compared the technical success rate, intra-operator reproducibility and liver stiffness values. 【Results】 The success rates of STE and 2D-SWE were 100%(106/106) and 96.2%(102/106), respectively(χ2=2.320, P=0.128), with four 2D-SWE examination failures in four patients with liver cirrhosis. Compared with those assessed by 2D-SWE, liver stiffness values assessed by STE were higher [5.83(5.30~ 6.37) kPa vs. 5.00(4.80~5.20) kPa, Z=4.419, P<0.001] in the healthy group, but lower [15.82(11.71~25.02) kPa vs. 18.50(11.95~29.93) kPa, Z=-2.981, P=0.003] in the liver cirrhosis group. The Spearman's rank correlation coefficient of STE and 2D-SWE was 0.896(95%CI: 0.849~0.928, P<0.001) . 【Conclusion】 With equally good reproducibility, STE is superior to 2D-SWE due to its higher success rate and better penetration especially in patients with cirrhosis. The liver stiffness values assessed by STE and 2D-SWE are not equivalent, which deserves our special attention in clinical application.
