Research progress on detection technology of pathogens in ticks
10.19428/j.cnki.sjpm.2022.21929
- VernacularTitle:蜱内病原体检测技术研究进展
- Author:
Wenbo ZENG
1
;
Zixin WEI
1
;
Yuan FANG
1
;
Tiange JIANG
2
;
Tian HANG
2
;
Yi ZHANG
1
Author Information
1. National Institute of Parasitic Diseases，Chinese Center for Disease Control and Prevention （Chinese Center for Tropical Diseases Research），NHC Key Laboratory of Parasite and Vector Biology，WHO Collaborating Center for Tropical Diseases，National Center for International Research on Tropical Diseases，Shanghai 200025，China
2. School of Global Health，Shanghai Jiao Tong University School of Medicine and Chinese Center for Tropical Diseases Research，Shanghai 200025，China
- Publication Type:Review
- Keywords:
metagenomics;
next generation sequencing;
shotgun sequencing;
amplicon sequencing;
PCR;
metavirome
- From:
Shanghai Journal of Preventive Medicine
2022;34(8):825-832
- CountryChina
- Language:Chinese
-
Abstract:
Ticks are the second most harmful infectious agent in the world after mosquitoes and can transmit a variety of pathogens. The surveillance of pathogen in ticks is one of the important means for the prevention and control of tick-borne diseases and tick-borne pathogens. This paper reviewed the literature published in the past two decades on the principles， advantages， disadvantages and applications of current tick pathogen detection technologies. The paper introduced the development and application of various PCR technologies， and looks forward to the future direction. Finally， it points out that metagenomics represented by high-throughput sequencing will become the mainstream development direction of pathogen detection technology in the future.
