Comparison and correlation of choroidal parameters in children and adolescents with different refractive status
10.3980/j.issn.1672-5123.2022.10.17
- VernacularTitle:不同屈光状态儿童及青少年的脉络膜参数比较及与眼球生物学参数相关性
- Author:
Feng-Tao JI
1
;
Hui WANG
1
;
Zhi-Min WANG
1
;
Wei DAI
1
;
Qin WANG
1
;
Yong-Rong LI
1
;
Rong-Feng LIAO
1
Author Information
1. Department of Ophthalmology, the First Affiliated Hospital of Anhui Medical University, Hefei 230022, Anhui Province, China; the Second People's Hospital of Hefei;Hefei Hospital Affiliated to Anhui Medical University, Hefei 230011, Anhui Province, China
- Publication Type:Journal Article
- Keywords:
myopia;
children and adolescents;
choroidal vascularity index;
binarization;
enhanced depth imaging-optical coherence tomography
- From:
International Eye Science
2022;22(10):1682-1686
- CountryChina
- Language:Chinese
-
Abstract:
AIM:To compare the choroidal parameters in children and adolescents with different refractive status, and to investigate the associations between ocular biometrics and choroidal parameters.METHODS:A cross sectional study. A total of 121 healthy children and adolescents(121 right eyes)aged 3-18 years treated in the Second People's Hospital of Hefei were collected. The data were divided into three groups according to spherical equivalent refraction(SER): emmetropia(-0.500.05). TCA, LA, SA, CT and CVI were found to be statistically different among the three groups after age correction(all P<0.001), and there were differences in pairwise comparisons of TCA, LA, SA and CT among the three groups(all P<0.001), which were the highest in emmetropic eyes and lowest in moderate-to-high myopic eyes, However, the CVI in pairwise comparisons among the three groups showed that only the moderate-to-high myopia group was significantly lower than the emmetropic group(P=0.014). Multiple regression analysis showed that the LA was significantly associated with SER(P=0.020), whereas CT were significantly associated with the axial length(AL)(P=0.028).CONCLUSIONS: The choroidal LA and CVI tend to decrease in children and adolescents with higher myopia, indicating that the decrease of sub-foveal choroidal blood flow may be related to the progression of myopia.
