Impact of multi-leaf collimator positioning accuracy on quality control of volumetric modulation arc therapy plan for cervical cancer treated with Elekta linear accelerator.
10.12122/j.issn.1673-4254.2022.07.19
- Author:
Jian LIANG
1
;
Feng Zi YU
2
;
Jin Han ZHU
2
;
Ting SONG
1
Author Information
1. School of Biomedical Engineering, Southern Medical University, Guangzhou 510515, China.
2. State Key Laboratory of Oncology in South China//Department of Radiotherapy, Sun Yat-sen University Cancer Center, Guangzhou 510060, China.
- Publication Type:Journal Article
- Keywords:
Autocal;
cervical cancer;
multi-leaf collimator;
plan verification;
volumetric modulation arc therapy
- MeSH:
Female;
Humans;
Particle Accelerators;
Quality Control;
Radiotherapy Dosage;
Radiotherapy Planning, Computer-Assisted/methods*;
Radiotherapy, Intensity-Modulated/methods*;
Uterine Cervical Neoplasms/radiotherapy*
- From:
Journal of Southern Medical University
2022;42(7):1089-1094
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To investigate the influence of positioning accuracy of the multi-leaf collimators (MLC) on the passing rate of the plan dose verification for volumetric modulation arc therapy (VMAT) of cervical cancer using an Elekta linear accelerator.
METHODS:The dose distributions were measured using Sun Nuclear's Mapcheck and Arccheck semiconductors matrix before and after MLC calibration in30 cervical cancer patients undergoing VMAT. Dosimetric comparisons were performed with 2D and 3D gamma passing rates of 3%, 3 mm and 2%, and 2 mm. The 3D gamma distribution was reconstructed with respect to the patient's anatomy using 3DVH software to evaluate the possible influence of MLC positioning accuracy.
RESULTS:Before and after MLC calibration, the gamma passing rates of Mapcheck were (88.80±1.81)% and (99.25 ± 0.53)% under 3% and 3 mm standard, respectively, with an average increase of 10.45%. The corresponding gamma passing rates of Arccheck were (87.61±1.98)% and (98.13±0.99)%, respectively, with an average increase of 10.52%. The gamma passing rates of 3DVH were (89.87±2.28)% and (98.3±1.15)%, respectively, with an average increase of 8.43%.
CONCLUSION:The MLC positioning accuracy is one of the main factors influencing dosimetric accuracy of VMAT for cervical cancer. The application of Autocal software facilitates MLC calibration and improves the accuracy and safety of VMAT delivery for cervical cancer.
