Modern research thoughts and methods on bio-active components of TCM formulae.
10.1016/S1875-5364(22)60206-1
- Author:
Yu-Ping TANG
1
;
Ding-Qiao XU
2
;
Shi-Jun YUE
2
;
Yan-Yan CHEN
2
;
Rui-Jia FU
2
;
Xue BAI
2
Author Information
1. Key Laboratory of Shaanxi Administration of Traditional Chinese Medicine for TCM Compatibility, State Key Laboratory of Research & Development of Characteristic Qin Medicine Resources (Cultivation), Shaanxi Key Laboratory of Chinese Medicine Fundamentals and New Drug Research, Shaanxi Collaborative Innovation Center of Chinese Medicinal Resource Industrialization, Shaanxi University of Chinese Medicine, Xi'an 712046, China. Electronic address: yupingtang@sntcm.edu.cn.
2. Key Laboratory of Shaanxi Administration of Traditional Chinese Medicine for TCM Compatibility, State Key Laboratory of Research & Development of Characteristic Qin Medicine Resources (Cultivation), Shaanxi Key Laboratory of Chinese Medicine Fundamentals and New Drug Research, Shaanxi Collaborative Innovation Center of Chinese Medicinal Resource Industrialization, Shaanxi University of Chinese Medicine, Xi'an 712046, China.
- Publication Type:Review
- Keywords:
Bio-active component;
Chinese medicine;
Morden research methods;
TCM formulae
- MeSH:
Biological Products;
Drugs, Chinese Herbal/chemistry*;
Medicine, Chinese Traditional/methods*;
Metabolomics;
Proteomics
- From:
Chinese Journal of Natural Medicines (English Ed.)
2022;20(7):481-493
- CountryChina
- Language:English
-
Abstract:
TCM formulae are the important guidances for clinical application of traditional Chinese medicines, which follow the principles of diagnosis and treatment in TCM. Elucidating the bio-active components of TCM formulae is the key to the modernization and internationalization of traditional Chinese medicines. With the rapid development of modern instruments and technology, many new theories, methods and strategies are emerging, which upgrade the research of TCM formulae into a higher level. Only when the medicinal efficacy, bio-active components, function mechanism of TCM formulae are understood, we can guarantee TCM safety and quality control. In this paper, we summarized the latest modern research thoughts and methods on bio-active components of TCM formulae including formula decomposition study, serum pharmacology and serum pharmacochemistry, association analysis, biochromatography, network pharmacology, metabolomics and proteomics, so as to provide reference for the research and development of TCM in the future.
