Two cases of late-onset cardiovascular toxicities after a single injection of local anesthetics during supraclavicular brachial plexus block - A report of two cases -
	    		
		   		
		   			
		   		
	    	
    	- Author:
	        		
		        		
		        		
			        		Ji Yeon KIM
			        		
			        		
			        		
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			        		Beom Il PARK
			        		
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			        		Min Hee HEO
			        		
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			        		Kyoung Woo KIM
			        		
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			        		Sang-Il LEE
			        		
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			        		Kyung-Tae KIM
			        		
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			        		Won Joo CHOE
			        		
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			        		Jang Su PARK
			        		
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			        		Jun Hyun KIM
			        		
			        		
		        		
		        		
		        		
			        		
			        		Author Information
			        		
 - Publication Type:Case Report
 - From:Anesthesia and Pain Medicine 2022;17(2):228-234
 - CountryRepublic of Korea
 - Language:English
 - Abstract: Local anesthetics systemic toxicity (LAST) is a grave complication of regional anesthesia that usually occurs immediately after local anesthetics injection. Here, we report on rare late-onset toxicity cases after supraclavicular brachial plexus blocks. Case: Two patients underwent surgery for radius fractures. We used lidocaine 100 mg and ropivacaine 150 mg for blocking and infused dexmedetomidine for intraoperative sedation. The 63-year-old male patient’s blood pressure dropped to 87/60 mmHg after 3 h 15 min after blocking. Ventricular fibrillation occurred 10 min later. After five defibrillations, electrocardiography showed ventricular tachycardia that was normalized through one cardioversion. The 54-year-old female patient’s heart rate decreased to 35 beats/min 2 h 30 min after blocking. Her vital signs returned to normal after administering atropine, ephedrine, epinephrine, and lipid emulsion. Conclusions: Physicians should remember that LAST may occur long after local anesthetic injection and be aware of factors that may adversely affect the course of LAST.
 
            