Association between hyperuricemia and hypertriglyceridemic waist phenotype in children and adolescents in Inner Mongolia
10.16835/j.cnki.1000-9817.2022.07.027
- VernacularTitle:内蒙古儿童青少年高三酰甘油腰围表型与高尿酸血症的关系
- Author:
CAO Ning, LI Lehui, ZHANG Nan, NIU Liwei, LYU Haiming, ZHANG Xingguang
1
Author Information
1. School of Public Health, Inner Mongolia Medical University, Hohhot(010110), China
- Publication Type:期刊文章
- Keywords:
Hyperuricemia;
Prevalence;
Regression analysis;
Child;
Adolescent
- From:
Chinese Journal of School Health
2022;43(7):1075-1078
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To investigate the prevalence and association of hyperuricemia (HUA) and hypertriglyceridemic Waist (HTW) phenotype in children and adolescents aged 6-17 years in Inner Mongolia, providing a basis for the prevention and treatment of hyperuricemia in adolescents in Inner Mongolia.
Methods:A total of 2 175 students of primary, junior high, and senior high school students from eight counties (districts) in Inner Mongolia were chosen and received a questionnaire survey, physical examination, and laboratory test by used a multi stage stratified random sampling approach. The association between the HTW phenotype and HUA was analyzed using binary Logistic regression.
Results:The prevalence of the HTW phenotype was 2.1%, with boys(2.5%) higher than that of girls(1.6%) ( χ 2=14.50, P<0.05). The average SUA level of the participants was 308.00 (259.00, 371.00) mmol/L, with a statistically significant sex difference(Z=-9.87, P<0.05). The prevalence of HUA was 21.1%. The frequency of HUA in the HTW phenotype(44.4%) was higher than in other phenotypes, followed by enlarged waist (EW) phenotype. After controlling for associated variables, the EW phenotypes (OR=1.76，95%CI=1.26-2.47) and HTW phenotypes (OR=2.25, 95%CI=1.12-4.52) were associated with higher risk for HUA(P<0.05).
Conclusion:In Inner Mongolia, the prevalence of HUA in children and adolescents aged 6-17 years is high, and there shows a positive association between the HTW phenotype and hyperuricemia. For the prevention of hyperuricemia, more attention should be paid to children and adolescents with HTW phenotype.
