Correlation analysis of 3D-FLAIR MRI characteristics of the inner ear and vestibular function in the patients with vestibular neuritis.
10.3760/cma.j.cn115330-20210203-00056
- VernacularTitle:前庭神经炎患者内耳3D-FLAIR MRI特点与前庭功能相关性分析
- Author:
Hui Rong JIAN
1
;
Na HU
2
;
Xiao Fei LI
1
;
Ya Feng LYU
1
;
Ya Wei LI
1
;
Zhao Min FAN
1
;
Hai Bo WANG
1
;
Dao Gong ZHANG
1
Author Information
1. Department of Vertigo Disease, Shandong Provincial ENT Hospital, Cheeloo College of Medicine, Shandong University, Jinan 250022, China Shandong Institute of Otolaryngology, Jinan 250022, China.
2. Medical Imaging Center, Shandong Provincial ENT Hospital, Cheeloo College of Medicine, Shandong University, Jinan 250022, China.
- Publication Type:Journal Article
- MeSH:
Caloric Tests;
Female;
Humans;
Imaging, Three-Dimensional/methods*;
Magnetic Resonance Imaging/methods*;
Male;
Vestibular Neuronitis/diagnosis*;
Vestibule, Labyrinth
- From:
Chinese Journal of Otorhinolaryngology Head and Neck Surgery
2022;57(5):578-583
- CountryChina
- Language:Chinese
-
Abstract:
Objective: The characteristics of 3D-FLAIR MRI images of the inner ear of patients with vestibular neuritis were preliminarily studied to explore the possible pathogenesis of vestibular neuritis, and the correlation analysis was conducted in combination with vestibular function to provide a basis for accurate diagnosis of vestibular neuritis. Methods: A total of 36 patients with vestibular neuritis (VN) from December 2019 to October 2020 were collected from the Vertigo Department of Shandong Provincial ENT Hospital, Cheeloo College of Medicine, Shandong University. There were 36 cases (18 females, 18 males) with unilateral acute vestibular neuritis, 17 cases of left ear and 19 cases of right ear. According to the results of 3D-FLAIR MRI in the inner ears, the patients were divided into the enhanced group and the non-enhanced group (the health side served as the normal control group). The results of vestibular function examination in the two groups were compared. SPSS19.0 software was used for statistical processing to analyze the relationship between the vestibular function and the characteristics of 3D-FLAIR imaging in the inner ears. Results: Abnormal enhancement of 3D-FLAIR was found in 31 cases (86.1%) of the 36 cases, including 14 cases of both vestibular nerve and vestibular terminal organ enhancement, eight cases of superior vestibular nerve enhancement alone, seven cases of vestibular terminal organ enhancement alone, and two cases of cochlear enhancement alone. Observation of abnormal reinforcement of vestibular nerve showed: twenty-one cases of superior vestibular nerve reinforcement, one case of superior and inferior vestibular nerve reinforcement. No abnormalities were found in 3D-FLAIR of inner ear in 5 cases. According to the analysis of vestibular function results, there were 19 cases (52.8%) with total vestibular involvement, sixteen cases (44.4%) with superior vestibular involvement alone, and one case (2.8%) with inferior vestibular involvement alone. Comparison of vestibular function between the five cases (non-enhancement group) and the 31 cases (enhanced group) in the 3D-FLAIR group of the inner ears showed that the CP values of caloric tests in the enhanced group were higher (60.81±3.49 vs 34.12±7.37), with statistically significant difference (t=-2.898, P<0.01). Conclusion: In patients with vestibular neuritis, 3D-FLAIR MRI scan of the inner ear provides visual imaging evidence for clinical practice, considering that the lesion site of vestibular neuritis is not only in the vestibular nerve, but also in the vestibular end organ. Patients with 3D-FLAIR enhanced in the inner ear may have more significant vestibular function damage.
