Research progress of dental pulp stem cells for peripheral nerve injury repair.
10.3760/cma.j.cn112144-20211214-00546
- VernacularTitle:牙髓干细胞修复周围神经损伤的研究进展
- Author:
Xiao Dan MU
1
;
Hua Wei LIU
1
;
Yong Feng LI
1
;
Lei XIANG
1
;
Min HU
1
Author Information
1. Department of Oral and Maxillofacial Surgery, General Hospital of Chinese PLA, Beijing 100853, China.
- Publication Type:Review
- MeSH:
Cell Differentiation;
Dental Pulp;
Humans;
Peripheral Nerve Injuries;
Quality of Life;
Stem Cells
- From:
Chinese Journal of Stomatology
2022;57(2):196-201
- CountryChina
- Language:Chinese
-
Abstract:
Peripheral nerve injuries are mainly related to severe trauma, fracture and tumor surgery, leading to reduced quality of life and impaired physical and mental health. The repair of peripheral nerve still faces great challenges in clinic, and the research on the regeneration and repair of peripheral nerve has become a hot issue in related disciplines. Cell therapy plays an irreplaceable role in tissue regeneration and repair. Schwann cells are ideal cells for peripheral nerve repair, but their limited sources inhibit the clinical application. Dental pulp stem cells are derived from neural crest, which provides a new cell source for nerve regeneration. The purpose of this article is to review the research progress of dental pulp stem cells for peripheral nerve repair.
