Etiology and epidemiology of hand, foot and mouth disease in China.
	    		
		   		
		   			
		   		
	    	
    	 
    	10.3760/cma.j.cn112338-20211012-00788
   		
        
        	
        		- VernacularTitle:手足口病病原学和流行病学研究进展
 
        	
        	
        	
        		- Author:
	        		
		        		
		        		
			        		Jing ZHANG
			        		
			        		
			        		
			        			1
			        			
			        		
			        		
			        		
			        		
			        		;
		        		
		        		
		        		
			        		Xiu Hui LI
			        		
			        		
			        		
			        			2
			        			
			        		
			        		
			        		
			        		
			        		;
		        		
		        		
		        		
			        		Li LI
			        		
			        		
			        		
			        			2
			        			
			        		
			        		
			        		
			        		
			        		;
		        		
		        		
		        		
			        		Xiao Fei SHANG
			        		
			        		
			        		
			        			2
			        			
			        		
			        		
			        		
			        		
			        		
		        		
		        		
		        		
		        		
		        			
			        		
			        		Author Information
			        		
		        		
		        		
			        		
			        		
			        			1. Division of Infectious Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing 102206, China.
			        		
			        			2. Integrated Traditional Chinese and Western Medicine Center, Beijing Youan Hospital of Capital Medical University, Beijing 100069, China.
			        		
		        		
	        		
        		 
        	
        	
        	
        		- Publication Type:Journal Article
 
        	
        	
            
            	- MeSH:
            	
	        			
	        				
	        				
				        		
					        		Child;
				        		
			        		
				        		
					        		China/epidemiology*;
				        		
			        		
				        		
					        		Encephalitis;
				        		
			        		
				        		
					        		Enterovirus;
				        		
			        		
				        		
					        		Enterovirus A, Human;
				        		
			        		
				        		
					        		Hand, Foot and Mouth Disease/epidemiology*;
				        		
			        		
				        		
					        		Humans
				        		
			        		
	        			
	        			
            	
            	
 
            
            
            	- From:
	            		
	            			Chinese Journal of Epidemiology
	            		
	            		 2022;43(5):771-783
	            	
            	
 
            
            
            	- CountryChina
 
            
            
            	- Language:Chinese
 
            
            
            	- 
		        	Abstract:
			       	
			       		
				        
				        	Hand, foot and mouth disease (HFMD) has been widespread in the world, and caused fever, rashes and other clinical symptoms of children, and sometimes inducing respiratory failure, brainstem encephalitis, and other complications, even death. The disease is mainly caused by enterovirus 71 (EV-A71) and coxsackievirus 16 (CV-A16). Since 2013, the proportion of HFMD cases caused by other enteroriruses has gradually increased, causing severe and even fatal cases. This paper summarizes the research progress in the epidemiological and etiological characteristics of HFMD in China since 2008.