Epidemiological characteristics and spatiotemporal clustering of hepatitis A in Zhejiang Province from 2010 to 2019.
10.3760/cma.j.cn112150-20210406-00330
- VernacularTitle:浙江省2010—2019年甲型肝炎流行特征和时空聚集性分析
- Author:
Yang ZHOU
1
;
Ming Yong TAO
2
;
Zhao Jun LU
3
;
Rui YAN
1
;
Xuan DENG
1
;
Xue Wen TANG
1
;
Yao ZHU
1
;
Han Qing HE
1
;
Ya Ping YAO
4
Author Information
1. Department of Immunization Program, Zhejiang Provincial Center for Disease Control and Prevention, Hangzhou 310051, China.
2. School of Medical, Ningbo University, Ningbo 315000, China.
3. School of Public Health, Zhejiang Chinese Medical University, Hangzhou 310053, China.
4. Department of Science Research and Information Management, Zhejiang Provincial Center for Disease control and Prevention, Hangzhou 310051, China.
- Publication Type:Journal Article
- MeSH:
China/epidemiology*;
Cluster Analysis;
Female;
Hepatitis A/epidemiology*;
Humans;
Incidence;
Male;
Middle Aged;
Spatial Analysis
- From:
Chinese Journal of Preventive Medicine
2022;56(4):459-463
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To analyze the epidemiological characteristics and spatiotemporal clustering of hepatitis A in Zhejiang Province from 2010 to 2019. Methods: The data of hepatitis A incidence in Zhejiang Province from 2010 to 2019 were collected from the infectious disease surveillance system of China Information System for Disease Control and Prevention. ArcGIS 10.7 software was used for spatial autocorrelation analysis. SaTScan 9.6 software was used for spatiotemporal scanning analysis. SPSS 25.0 software was used for additional analysis. Results: Zhejiang Province has reported 5 465 cases of hepatitis A in 2010-2019 years, with an average annual incidence rate of 1.00/100 000, and periodicity and seasonality are not obvious. The incidence of male was higher than that of female (P=0.023), and the highest incidence rate was 50-59 years old. Spatial autocorrelation analysis showed that there was a positive spatial correlation between the incidence of hepatitis A in Zhejiang Province from 2010 to 2017, with the weakest correlation in 2010 (Moran's I =0.103, Z=1.769, P=0.049), and the strongest correlation in 2016 (Moran's I=0.328, Z=4.979, P=0.001). Spatiotemporal scanning analysis showed that there was spatial aggregation of hepatitis A in Zhejiang Province from 2010 to 2019, with a total of three aggregation areas identified. Among them, the mostly aggregation area was concentrated in Xiangshan county of Ningbo city, which covered 10 counties (cities and districts), including Ninghai county and Yinzhou district, and appeared from January 1 to June 30, 2012. Conclusion: The incidence level of hepatitis A in Zhejiang Province shows a stable fluctuation trend from 2010 to 2019, and the seasonal regularity is not obvious. The population group aged 50-59 years old is the key population. There is spatial aggregation in the epidemic situation of hepatitis A. Targeted prevention and control measures of hepatitis A should be done based on the law of spatiotemporal aggregation and local incidence.
