Correlation of intraocular pressure changes and the surgical parameters after SMILE for high myopia
	    		
		   		
		   			
		   		
	    	
    	 
    	10.3980/j.issn.1672-5123.2022.8.33
   		
        
        	
        		- VernacularTitle:高度近视SMILE术后眼压变化与手术参数的相关性
 
        	
        	
        	
        		- Author:
	        		
		        		
		        		
			        		Na-Na ZHANG
			        		
			        		
			        		
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			        		Xin-Zhi SONG
			        		
			        		
			        		
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			        		Yong JIN
			        		
			        		
			        		
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			        		Li-Yuan YANG
			        		
			        		
			        		
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			        		Mei-Ling QIAN
			        		
			        		
			        		
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			        		Jun YANG
			        		
			        		
			        		
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			        		Author Information
			        		
		        		
		        		
			        		
			        		
			        			1. Department of Optometric Center, Gansu Provincial Hospital, Lanzhou 730000, Gansu Province, China
			        		
		        		
	        		
        		 
        	
        	
        	
        		- Publication Type:Journal Article
 
        	
        	
        		- Keywords:
        			
	        			
	        				
	        				
			        		
				        		femtosecond laser small incision lenticule extraction(SMILE);
			        		
			        		
			        		
				        		high myopia;
			        		
			        		
			        		
				        		intraocular pressure;
			        		
			        		
			        		
				        		the surgical parameters;
			        		
			        		
			        		
				        		correlation
			        		
			        		
	        			
        			
        		
 
        	
            
            
            	- From:
	            		
	            			International Eye Science
	            		
	            		 2022;22(8):1407-1410
	            	
            	
 
            
            
            	- CountryChina
 
            
            
            	- Language:Chinese
 
            
            
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		        	Abstract:
			       	
			       		
				        
				        	 AIM: To analyze the correlation of changes in non-contact intraocular pressure(IOPNCT)and the surgical parameters after femtosecond laser small incision lenticule extraction(SMILE)for high myopia.MOTHODS:A retrospective analysis, the clinical data of 98 patients(196 eyes)with high myopia were operated SMILE in the optometric center of Gansu Provincial Hospital from January 2018 to July 2019 were analyzed. The change of IOPNCT before and after operation was observed, and recorded the optical zone(OZ), lenticule thickness(LT), cap thickness(CT)and residual stromal thickness(RST)and the correlation with the change value of IOPNCT(△IOPNCT, △IOPNCT=IOPpreoperative-IOP postoperative at 6mo).RESULTS:After operation at 1d, 1wk, 1,3 and 6mo, the group of patients with IOPNCT(10.84±2.14,11.00±2.19,10.65±2.43,10.45±2.04,10.61±1.39mmHg)and the preoperative(16.79±1.65mmHg)comparison have a difference(P<0.001).The optical zone and lenticule thickness were positively correlated with △IOPNCT respectively(r=0.1537, 0.8161, all P<0.05). The cap thickness and residual stromal thickness were negatively correlated with △IOPNCT respectively(r=-0.8362, -0.3351, all P<0.0001). Introduce the above related factors into a multiple linear regression analysis model. The regression coefficients of variables are statistical significane. The regression equation was Y=16.189+0.227X1+0.032X2-0.083X3-0.007X4(Y=△IOPNCT, X1=OZ, X2=LT, X3=CT, X4=RST). The equation was statistically significant(F=195.704, P<0.001), and the regression model coefficient of determination R2=0.901.CONCLUSION:The intraocular pressure changes after SMILE with high myopic were correlated with optical zone, lenticule thickness, cap thickness and residual stromal thickness. The regression equation would provide reference to evaluation the real intraocular pressure after SMILE in clinic.