Association between anesthesia regimen and postoperative infection in patients undergoing cardiac surgery: A retrospective cohort study
- VernacularTitle:麻醉药物对成人心脏手术患者术后感染影响的回顾性队列研究
- Author:
Wei TIAN
1
,
2
;
Ying CHEN
3
,
4
;
Hong YU
5
;
Liang JIN
3
,
6
;
Hai YU
5
Author Information
1. Department of Anesthesiology, West China Hospital, Sichuan University, Chengdu, 610041, P. R. China；
2. Department of Anesthesiology, First People's Hospital of Neijiang City, Neijiang, 641000, Sichuan, P. R. China
3. Department of Anesthesiology, West China Hospital, Sichuan University, Chengdu, 610041, P. R. China;
4. Department of Anesthesiology, Liangshan Hospital of Integrated Traditional Chinese and Western Medicine, Liangshan, 615000, Sichuan, P. R. China
5. Department of Anesthesiology, West China Hospital, Sichuan University, Chengdu, 610041, P. R. China
6. Department of Anesthesiology, Leshan People's Hospital, Leshan, 614000, Sichuan, P. R. China
- Publication Type:Journal Article
- Keywords:
Volatile anesthetics;
sevoflurane;
desflurane;
intravenous anesthetics;
propofol;
cardiopulmonary bypass;
cardiac surgery;
postoperative infection
- From:
Chinese Journal of Clinical Thoracic and Cardiovascular Surgery
2022;29(05):585-591
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the association between anesthesia regimen (volatile or intravenous anesthetics) and postoperative infection in adult cardiac patients undergoing cardiac surgery. Methods The clinical data of 496 elective adults undergoing cardiac surgery under cardiopulmonary bypass from June 2019 to June 2020 in West China Hospital of Sichuan University were retrospectively analyzed, including 251 females and 245 males with an average age of 54.1±11.4 years. American Society of Anesthesiologists grade was Ⅰ-Ⅲ. There were 243 patients in a volatile group with sevoflurane or desflurane, and 253 patients in an intravenous anesthesia group with propofol. The primary outcome was the incidence of infection within 30 days after cardiac surgery, including pulmonary infection, surgical site infection, sepsis, and urinary tract infection. The secondary outcomes were duration of mechanical ventilation, incidence of reintubation, ICU stay, postoperative length of hospital stay and total hospitalization cost. Results A total of 155 (31.3%) patients developed postoperative infection within 30 days, with an incidence of 32.9% in the volatile group and 29.6% in the intravenous anesthesia group. There was no statistical difference in the incidence of infection (RR=1.111, 95%CI 0.855 to 1.442, P=0.431) or the secondary outcomes (P>0.05) between the two groups. Conclusion The anesthesia regimen (volatile or intravenous anesthetics) has no association with the risk of occurrence of postoperative infection in adult patients undergoing elective cardiac surgery with cardiopulmonary bypass.
