One case of Mycoplasma hominis-related intracranial infection after craniocerebral injury

VernacularTitle:颅脑损伤后人型支原体颅内感染1例
Author: Lijuan CHEN ¹ ; Liheng ZHENG ; Jing LIN ; Xue HUANG
Author Information

1. 福建省仙游县总医院检验科，莆田　351254
Keywords: Mycoplasma hominis; Craniocerebral trauma; Infection
From: Chinese Journal of Laboratory Medicine 2022;45(2):197-199
CountryChina
Language:Chinese
Abstract: The patient, a 50-year-old male, was admitted to the hospital on April 1, 2020 with the chief complaint of "confusion with vomiting for 1 hour due to falling from height ", and the emergency craniotomy was performed. Intermittent fever with a maximum temperature of 38 ℃ occurred 3 days after the surgery, and the inflammation indexes were all higher than the upper limit of the reference values. Recurrent fever remained despite after empirical anti-infection treatment. On April 12, the patient was treated with vancomycin combined with meropenem after cerebrospinal fluid specimens routine and biochemical tests suggested intracranial infection. After 48 hours of cultivating the cerebrospinal fluid and blood specimens, some small, clear, needle-like colonies were found and they were identified as Mycoplasma humanum by using 16S rRNA gene. Eventually, the patient died due to the severity of the disease and complications.