Mechanism of blood brain barrier in the pathogenesis and therapeutics of multiple sclerosis
10.3760/cma.j.cn113694-20210912-00631
- VernacularTitle:血脑屏障在多发性硬化发病及治疗中的作用机制
- Author:
Yan JIA
1
;
Yue HUANG
;
Jiewen ZHANG
;
Junkui SHANG
;
Mingfang ZHU
;
Xiaodi HAO
Author Information
1. 河南省人民医院神经内科，郑州450000
- Keywords:
Multiple sclerosis;
Blood brain barrier;
Pathogenesis;
Therapeutics
- From:
Chinese Journal of Neurology
2022;55(6):655-658
- CountryChina
- Language:Chinese
-
Abstract:
Multiple sclerosis (MS) is an idiopathic inflammatory demyelinating diseases of the central nervous system, the underlying cause of which has not been cleared. Previous studies have shown that the pathogenesis of MS is related to the destruction of blood brain barrier, furthermore the drugs used to treat MS have a certain protective effect on the function of blood brain barrier. Therefore, this review combines the research progress at home and abroad to clarify the relationship between the blood brain barrier and MS in pathogenesis and treatment, proposing possible orientation of development.
