The progress on the use of botulinum toxin type A therapy in Parkinson′s disease
	    		
		   		
		   			
		   		
	    	
    	 
    	10.3760/cma.j.cn113694-20210522-00359
   		
        
        	
        		- VernacularTitle:A型肉毒毒素治疗帕金森病研究进展
 
        	
        	
        	
        		- Author:
	        		
		        		
		        		
			        		Rongrong BAI
			        		
			        		
			        		
			        			1
			        			
			        		
			        		
			        		
			        		
			        		;
		        		
		        		
		        		
			        		Yali TANG
			        		
			        		;
		        		
		        		
		        		
			        		Lazhen SHE
			        		
			        		;
		        		
		        		
		        		
			        		Chunyu WANG
			        		
			        		
		        		
		        		
		        		
		        		
		        			
			        		
			        		Author Information
			        		
		        		
		        		
			        		
			        		
			        			1. 中南大学湘雅二医院神经病学科,长沙 410011
			        		
		        		
	        		
        		 
        	
        	
        	
        	
        		- Keywords:
        			
	        			
	        				
	        				
			        		
				        		Botulinum toxin, type A;
			        		
			        		
			        		
				        		Parkinson disease;
			        		
			        		
			        		
				        		Therapeutic uses
			        		
			        		
	        			
        			
        		
 
        	
            
            
            	- From:
	            		
	            			Chinese Journal of Neurology
	            		
	            		 2022;55(1):70-76
	            	
            	
 
            
            
            	- CountryChina
 
            
            
            	- Language:Chinese
 
            
            
            	- 
		        	Abstract:
			       	
			       		
				        
				        	Botulinum toxin type A (BTX A) has gain widespread use in various neurological conditions, characterized by safe injection and less side-effect. This review will examine the current research of BTX A in the following aspects: mechanism, location, dose and outcome, which manifests the safety and efficacy data of BTX A injection treatment to the symptoms of Parkinson disease, including refractory tremor, focal dystonia, loss of postural reflexes, sialorrhea, gastrointestinal symptoms and depressive disorder.