Research advances on undifferentiated connective tissue disease in pregnant women

VernacularTitle:未分化结缔组织病合并妊娠的研究进展
Author: Jing YUE ¹ ; Jianyu ZHANG ; Huimin WANG ; Jian CHEN ; Ting LI ; Xiaoyan CAI
Author Information

1. 广州医科大学附属第三医院风湿免疫科，广州　510170
Keywords: Connective tissue diseases; Undifferentiated connective tissue diseases; Autoantibodies; Pregnancy; Treatment
From: Chinese Journal of General Practitioners 2022;21(5):492-496
CountryChina
Language:Chinese
Abstract: Undifferentiated connective tissue disease (UCTD) has clinical and laboratory characteristics of connective tissue disorders, but it can not meet the diagnostic criteria of any specific disease. Pregnancy complicated with UCTD is one of the most common rheumatic diseases in women of childbearing age. UCTD will increase the risk of adverse events of pregnancy, such as spontaneous abortion, preeclampsia, fetal growth restriction, small for gestational age,recurrent implantation failure and so on. Pregnancy may lead to recurrence, aggravation and even serious complications of UCTD; multidisciplinary monitoring and appropriate treatment can improve the pregnancy outcome.