Upper limb lymphedema as the initial symptom of malignant disease
	    		
		   		
		   			
		   		
	    	
    	 
    	10.3760/cma.j.cn113855-20211129-00686
   		
        
        	
        		- VernacularTitle:以上肢淋巴水肿为首发表现的恶性肿瘤的临床分析
 
        	
        	
        	
        		- Author:
	        		
		        		
		        		
			        		Kun HAO
			        		
			        		
			        		
			        			1
			        			
			        		
			        		
			        		
			        		
			        		;
		        		
		        		
		        		
			        		Yuguang SUN
			        		
			        		;
		        		
		        		
		        		
			        		Song XIA
			        		
			        		;
		        		
		        		
		        		
			        		Jianfeng XIN
			        		
			        		;
		        		
		        		
		        		
			        		Kun CHANG
			        		
			        		;
		        		
		        		
		        		
			        		Chunkai YU
			        		
			        		;
		        		
		        		
		        		
			        		Li ZHANG
			        		
			        		;
		        		
		        		
		        		
			        		Bin LI
			        		
			        		;
		        		
		        		
		        		
			        		Wenbin SHEN
			        		
			        		
		        		
		        		
		        		
		        		
		        			
			        		
			        		Author Information
			        		
		        		
		        		
			        		
			        		
			        			1. 首都医科大学附属北京世纪坛医院淋巴外科,北京 100038
			        		
		        		
	        		
        		 
        	
        	
        	
        	
        		- Keywords:
        			
	        			
	        				
	        				
			        		
				        		Lymphedema;
			        		
			        		
			        		
				        		Upper extremity;
			        		
			        		
			        		
				        		Neoplasms
			        		
			        		
	        			
        			
        		
 
        	
            
            
            	- From:
	            		
	            			Chinese Journal of General Surgery
	            		
	            		 2022;37(5):358-360
	            	
            	
 
            
            
            	- CountryChina
 
            
            
            	- Language:Chinese
 
            
            
            	- 
		        	Abstract:
			       	
			       		
				        
				        	Objective:To investigate the diagnosis of malignancy with upper limb lymphedema as the initial sign and symptoms.Methods:Clinical data of 6 patients with malignant lymphedema admitted at the Department of Lymphatic Surgery, Beijing Shijitan Hospital, Capital Medical University, from May 2007, to Dec 2018 were retrospectively analyzed.Results:The age of these 6 patients ranged from 50 to 78 years. The time from the occurrence of lymphedema to the diagnosis of malignant tumors ranged from 1 month to 15 years. Limb swelling occurred in all 6 cases. Local lymphadenopathy occurred in 4 cases and limb paresthesia occurred in 2 cases. Pathological diagnosis showed that the tumor originated from epithelial tissue in 3 cases, mesenchymal tissue in 2 cases and lymphatic system in 1 case. Pathological diagnosis showed that the tumor originated from epithelial tissue in 3 cases, mesenchymal tissue in 2 cases and lymphatic system in 1 case.Conclusions:To avoid delays in the diagnosis and therapy of malignant lymphedema, physicians should actively look for signs or symptoms of lymphedema during the follow-up period and promptly manage patients developing problems.