Clinical factors influencing the effect of anti-reflux surgery for gastroesophageal reflux disease
10.3760/cma.j.cn113855-20210706-00413
- VernacularTitle:影响胃食管反流病外科治疗疗效的临床因素分析
- Author:
Bin WANG
1
;
Wei ZHANG
;
Sheng LIU
;
Xiaoxia CEN
;
Ming QIU
Author Information
1. 海军军医大学第二附属医院甲乳疝外科,上海 200003
- Keywords:
Gastroesophageal reflux;
Proton pump inhibitor;
Depression;
Lower esophageal sphincter;
Hernia, hiatal
- From:
Chinese Journal of General Surgery
2022;37(2):84-89
- CountryChina
- Language:Chinese
-
Abstract:
Objective:to analyze the risk factors for the side effect of anti-reflux surgery for gastroesophageal reflux disease (GERD) with regards to relief of reflux symptom, dysphagia and postoperative satisfaction.Method:The incidence of disappointing chief complaint among 192 patients who underwent anti-reflux surgery was analyzed. The related independent risk factors were identified by multivariate analysis.Results:The incidence of non-relief of reflux symptom was approximately 21.8% (42 cases), of which the risk factors were identified as preoperative depression and long-term PPI administration. The incidence of persistent dysphagia was 7.3% (14 cases), of which the risk factors were identified as preoperative depression and weak peristalsis of esophageal body. The incidence of postoperative dissatisfaction was 26.0% (50 cases), of which the risk factors were identified as long-term PPI administration and moderate-severe depression. The GERD patients with hiatal hernia and low pressure of lower esophageal sphincter were more likely benefit from anti-reflux surgery and had a higher postoperative satisfaction rate.Conclusion:Hiatal hernia and low pressure of lower esophageal sphincter are the favorable factors predicting good result of anti-reflux surgery. Long-term PPI administration and preoperative depression is an indication for poor result of anti-reflux surgery.
