Clinical value of modified acute aortic dissection risk score in the early diagnosis of acute aortic dissection
	    		
		   		
		   			
		   		
	    	
    	 
    	10.3760/cma.j.issn.1008-6706.2022.01.005
   		
        
        	
        		- VernacularTitle:改良急性主动脉夹层风险评分在急性主动脉夹层早期诊断中的应用价值
 
        	
        	
        	
        		- Author:
	        		
		        		
		        		
			        		Wei CHEN
			        		
			        		
			        		
			        			1
			        			
			        		
			        		
			        		
			        		
			        		;
		        		
		        		
		        		
			        		Xinwei ZHOU
			        		
			        		;
		        		
		        		
		        		
			        		Jie XU
			        		
			        		;
		        		
		        		
		        		
			        		Fangying DONG
			        		
			        		;
		        		
		        		
		        		
			        		Ming ZHANG
			        		
			        		
		        		
		        		
		        		
		        		
		        			
			        		
			        		Author Information
			        		
		        		
		        		
			        		
			        		
			        			1. 嘉兴市第二医院急诊科,嘉兴 314000
			        		
		        		
	        		
        		 
        	
        	
        	
        	
        		- Keywords:
        			
	        			
	        				
	        				
			        		
				        		Aneurysm, dissecting;
			        		
			        		
			        		
				        		Aorta;
			        		
			        		
			        		
				        		Acute aortic dissection risk score;
			        		
			        		
			        		
				        		Blood pressure;
			        		
			        		
			        		
				        		Chest pain;
			        		
			        		
			        		
				        		Early diagnosis;
			        		
			        		
			        		
				        		Multivariate analysis;
			        		
			        		
			        		
				        		D-2 polymer;
			        		
			        		
			        		
				        		Receiver ope
			        		
			        		
	        			
        			
        		
 
        	
            
            
            	- From:
	            		
	            			Chinese Journal of Primary Medicine and Pharmacy
	            		
	            		 2022;29(1):18-22
	            	
            	
 
            
            
            	- CountryChina
 
            
            
            	- Language:Chinese
 
            
            
            	- 
		        	Abstract:
			       	
			       		
				        
				        	Objective:To investigate the clinical value of modified acute aortic dissection risk score in the early diagnosis of acute aortic dissection (AAD).Methods:The general, clinical, and imaging data of 162 patients who complained of chest and back pain who received treatment between January 2019 and January 2021 in the Department of Emergency, The Second Hospital of Jiaxing, China were collected for this study. The included patients were divided into control (non-AAD, n = 120) and observation (AAD, n = 42) groups according to whether they were diagnosed with AAD. The indexes with statistical significance between the two groups were analyzed using multivariate logistic regression analysis. A score table was established according to the size of OR value. The modified AAD risk score was predicted using the receiver operating curve. Results:Multivariate logistic regression analysis showed that male sex, family history, sudden severe chest and back pain, bilateral blood pressure asymmetry, hypertension, abnormal ultrasound, and D-dimer level were independent risk factors for the diagnosis of AAD (statistical values = 7.84, 6.96, 7.04, 11.38, 7.12, 8.15, 15.07, 9.11, all P < 0.05). Taking the total score of 5 as the prediction standard, the specificity and sensitivity in the prediction of the occurrence of AAD were 84.94% and 95.43%, respectively. The area under the receiver operating curve regarding the modified AAD risk score was 0.909. Conclusion:The modified AAD risk score can be used to conveniently and quickly predict the occurrence of AAD and has a high predictive value. This study is highly innovative and scientific.