Case report of SAPHO syndrome in children
10.3760/cma.j.cn101070-20201127-01818
- VernacularTitle:儿童SAPHO综合征1例
- Author:
Xiaoyi SUN
1
;
Jing WANG
;
Han SONG
;
Shuzhen SUN
Author Information
1. 山东大学附属省立医院小儿肾脏风湿免疫科，济南 250021
- Keywords:
SAPHO syndrome;
Acne;
Arthritis;
Child
- From:
Chinese Journal of Applied Clinical Pediatrics
2022;37(6):459-461
- CountryChina
- Language:Chinese
-
Abstract:
Retrospective analysis.To report a child with synovitis, acne, pustulosis, hyperostosis, osteitis (SAPHO) syndrome admitted to the Department of Pediatric Nephrology and Rheumatology, Shandong Provincial Hospital, Cheeloo College of Medicine, Shandong University in March 2020.A 14-year-old boy presented to hospital due to acne for more than 2 months, fever for more than 50 days, and hip pain for 2 weeks.The patient was diagnosed and treated as acne combined with infection and arthritis in other hospitals for more than 2 months without remission.He was initially diagnosed as juvenile idiopathic arthritis, acne combined with infection on admission.The disease was aggravated even after medications of anti-infection and anti-inflammatory drugs.After multidisciplinary consultation, the patient was diagnosed as SAPHO syndrome.The patient recovered from medications of Celecoxib, Sulfasalazine, recombinant human tumor necrosis factor receptorⅡ: IgG Fc fusion protein and other drugs.SAPHO syndrome is rare, especially in children, which is easily misdiagnosed.This case report suggested that SAPHO should be considered in children with acne, especially those combined with arthritis.
