Mechanism of hepatocyte growth factor in childhood respiratory diseases
10.3760/cma.j.cn101070-20200812-01337
- VernacularTitle:肝细胞生长因子在儿童呼吸系统疾病中的作用机制
- Author:
Xiaoxu YUAN
1
;
Chunmei JIA
Author Information
1. 包头市第四医院（包头市儿童医院）儿科，包头 014030
- Keywords:
Hepatocyte growth factor;
Respiratory system;
Disease;
Mechanism;
Child
- From:
Chinese Journal of Applied Clinical Pediatrics
2022;37(2):157-160
- CountryChina
- Language:Chinese
-
Abstract:
Hepatocyte growth factor (HGF) is a mesenchymal-derived growth factor, which is widely used in the basic and clinical research of pediatric multi-system due to various biological functions.As a protective factor for lung tissues, HGF has significant biological effects on enhancing lung tissue development, stimulating DNA production of lung epithelial cells, repairing lung microvascular endothelial cells, inhibiting apoptosis induced by lung injury, and delaying pulmonary fibrosis.HGF is closely related to the occurrence and development of respiratory diseases in children.This study aims to review the physiological characteristics of HGF and the mechanism in children′s respiratory diseases.
