Clinical study on self-made Jianpi Zaoshi Anshen Decoction in the treatment of elderly chronic diarrhea of heart-spleen deficiency
10.3760/cma.j.cn115398-20210812-00122
- VernacularTitle:自拟健脾燥湿安神方治疗老年慢性腹泻心脾两虚证临床研究
- Author:
Yali LI
1
;
Zhihong GUO
;
Yuan TIAN
Author Information
1. 北京市东城区第一人民医院传统医学科，北京 100075
- Keywords:
Diarrhea;
Aged;
Heart spleen deficiency;
Self-made Jianpi Zaoshi Anshen Decoction
- From:
International Journal of Traditional Chinese Medicine
2022;44(5):526-529
- CountryChina
- Language:Chinese
-
Abstract:
Objective:TTo evaluate the clinical efficacy of self-made Jianpi Zaoshi Anshen Decoction on elderly patients with chronic diarrhea of heart-spleen deficiency.Methods:A total of 80 elderly patients with chronic diarrhea of heart-spleen deficiency who met the inclusion criteria were divided into the two groups by the random number table method, with 40 cases in each group. Control group was given pinaverium bromide tablets while observation group was treated with self-made Jianpi Zaoshi Anshen Decoction, and both groups were treated for 1 months. The TCM syndromes were scored before and after treatment, and Irritable Bowel Syndrome-Symptom Severity Scale (IBS-SSS) was used to evaluate the severity of intestinal symptoms. The adverse reactions during treatment were observed and the clinical efficacy was assessed.Results:The total effective rate was 92.5% (37/40) in observation group and was 75.0% (30/40) in control group respectively ( χ 2=4.50, P=0.034). The scores of abdominal pain, abdominal distension, abdominal pain frequency and impact on life in observation group after treatment were lower than those in control group ( t values were 5.32, 6.75, 4.37, 3.55, respectively, all Ps<0.001), and the scores of pond dilute stool, loss of appetite and anorexia, faint abdominal pain and physical fatigue were lower than those in control group ( t values were 4.38, 5.88, 7.41, 6.00, respectively, all Ps<0.001). During treatment, the incidence rate of adverse reactions was 15.0% (6/40) in observation group and that in control group was 25.0% (10/40) ( χ2=1.25, P=0.264). Conclusion:Self-made Jianpi Zaoshi Anshen Decoction for elderly patients with chronic diarrhea of heart-spleen deficiency can control the early disease condition, enhance the clinical efficacy and improve the clinical symptoms.
