Clinical study on self-made Yangyin Yiqi Quxie Decoction combined with fire-needle pricking collaterals and bloodletting for the rosacea patients with excessive heat of lung and stomach
10.3760/cma.j.cn115398-20210729-00266
- VernacularTitle:自拟养阴益气祛邪汤结合火针及刺络放血治疗玫瑰痤疮肺胃热盛证临床研究
- Author:
Li MA
1
;
Yongmei HUANG
;
Ping WANG
Author Information
1. 西宁市第一人民医院皮肤科，西宁 810000
- Keywords:
Acneiform eruptions;
Rosacea;
Pattern of heat exuberance in lung and stomach;
Self-made Yangyin Yiqi Quxie Decoction;
Fire needle therapy;
Bloodletting the
- From:
International Journal of Traditional Chinese Medicine
2022;44(5):521-525
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To evaluate the clinical efficacy of self-made Yangyin Yiqi Quxie Decoction combined with fire-needle pricking collaterals and bloodletting in the treatment of rosacea with excessive heat of lung and stomach syndrome.Methods:From February 2018 to February 2021, 120 patients with rosacea excessive heat of lung and stomach syndrome in our hospital who met the inclusion criteria were randomly divided into 2 groups by the two-color ball method, with 60 in each group. The control group was given conventional western medicine, fire-needle pricking collaterals and bloodletting therapy, while the study group was given self-made Yangyin Yiqi Quxie Decoction on the basis of the control group. Both groups were treated for 6 weeks. The clinical symptoms were scored before and after treatment, the levels of serum IL-6, IL-17 and IL-37 were detected by chemiluminescence method, the adverse reactions during treatment were recorded and the clinical efficacy was evaluated.Results:The total effective rate was 90.0% (54/60) in the study group and 70.0% (42/60) in the control group, and there was significant difference between the two groups ( χ2=7.50, P=0.006). After treatment, the levels of serum IL-6, IL-17 and IL-37 in the study group were significantly lower than those in the control group ( t values were 30.94, 9.73 and 14.84, respectively, all Ps<0.001), the scores of burning, pustules, pruritus, dryness, erythema, telangiectasia and the total scores in the study group were significantly lower than those in the control group ( t values were 5.68, 14.69, 10.35, 15.83, 13.44, 14.37 and 23.13, respectively, all Ps<0.001). There were no obvious adverse reactions in both groups during treatment. Conclusion:The self-made Yangyin Yiqi Quxie Decoction combined with fire-needle pricking collaterals and bloodletting can relieve the symptoms in patients with rosacea excessive heat of lung and stomach syndrome, reduce serum inflammatory cytokine levels, and improve clinical effects.
