Research progress on effective components and mechanisms of anti-depressive Chinese medicine.
10.19540/j.cnki.cjcmm.20211122.202
- Author:
Zhen-Guang SONG
1
;
Xiao-Qing ZHOU
1
;
Dong-Mei YAN
1
;
Li-Ping TANG
1
;
Fei WANG
1
;
Bin LI
1
Author Information
1. Workstation for Academician, Jiangxi University of Chinese Medicine Nanchang 330004, China.
- Publication Type:Journal Article
- Keywords:
Chinese medicine;
depression;
effective components;
mechanism;
research progress
- MeSH:
Drug-Related Side Effects and Adverse Reactions;
Drugs, Chinese Herbal/therapeutic use*;
Humans;
Medicine, Chinese Traditional;
Syndrome
- From:
China Journal of Chinese Materia Medica
2022;47(5):1184-1189
- CountryChina
- Language:Chinese
-
Abstract:
Since the pathogenesis of depression is complicated, the therapeutic effects of western medicine are poor accompanied by severe side effects. Chinese medicine has unique advantages in the treatment based on syndrome differentiation and contains many effective components against depression, including flavonoids, terpenes, phenylpropanoids, quinones, and alkaloids. These chemical components can delay the course of the disease, improve the curative effect, and reduce side effects of western medicine by regulating the biochemical abnormalities of monoamine neurotransmitters, brain tissue protein content, and internal environment as well as energy metabolism to make the treatment of Chinese medicine highlighted and recognized. This study systematically reviewed the effective components and mechanisms of anti-depressive Chinese medicine to inspire the rational development and utilization of new Chinese medicines against depression.