Sentinel Lymph Node Biopsy Versus Elective Neck Dissection: Long-Term Oncologic Outcomes in Clinically Node-Negative Tongue Cancer
- Author:
Woori PARK
1
;
Hokyung JIN
;
Yujin HEO
;
Han-Sin JEONG
;
Young-Ik SON
;
Man Ki CHUNG
;
Chung-Hwan BAEK
Author Information
- Publication Type:Original Article
- From:Clinical and Experimental Otorhinolaryngology 2022;15(1):107-114
- CountryRepublic of Korea
- Language:English
-
Abstract:
Objectives:. The aim of this study was to compare the long-term oncologic outcomes of sentinel lymph node biopsy (SLNB) versus elective neck dissection (END) in clinically node-negative (cN0) tongue cancer.
Methods:. This was a retrospective cohort study of patients with cN0 tongue cancer from a single institution, including 91 patients in the SLNB group and 120 patients in the END group.
Results:. The overall recurrence rate showed no significant difference between the two groups. The regional control rate was also comparable between the two groups (P=0.490). The 5-year recurrence-free survival (RFS) was slightly better in the SLNB group than in the END group (P=0.427). The 5-year overall survival (OS) rate was 89.9% in the SLNB group versus 91.9% in the END group (P=0.737). In a propensity-matched subgroup analysis, the type of neck management did not affect RFS or OS.
Conclusion:. SLNB showed non-inferior oncologic outcomes compared to END in patients with cN0 tongue squamous cell carcinoma.
