Early predictors for acute kidney injury in acute pancreatitis

VernacularTitle:急性胰腺炎发生急性肾损伤的早期预测指标
Author: Yan WANG ¹ ; Mingzheng LI ¹ ; Yufeng LIU ¹ ; Shiming WANG ²
Author Information

1. Graduate School, Shanxi Medical University, Taiyuan 030001, China
2. Department of General Surgery, The First Hospital of Shanxi Medical University, Taiyuan 030001, China
Publication Type:Reviews
Keywords: Pancreatitis, Acute Necrotizing; Acute Kidney Injury; Inflammation; Early Diagnosis
From: Journal of Clinical Hepatology 2022;38(5):1192-1197
CountryChina
Language:Chinese
Abstract: Acute pancreatitis (AP) is one of the common acute abdominal diseases of the digestive system, and early treatment to avoid aggravation to severe pancreatitis (SAP) is the key to guaranteeing prognosis. AP with acute kidney injury (AKI) can significantly increase the mortality rate of pancreatitis. Early diagnosis of AP with AKI is a top priority to reduce mortality rate. This article reviews the current studies on the early predictors for AKI in AP and briefly describes commonly used indicators (neutrophil-to-lymphocyte ratio, cystatin C, renal vascular resistance index, and neutrophil gelatinase-associated lipocalin) and other valuable indicators. It is pointed out that a combination of various markers based on their sensitivity and specificity has a promising future in the diagnosis of AKI in AP.