Advances in the clinical research on liver transplantation in treatment of acute-on-chronic liver failure
10.3969/j.issn.1001-5256.2022.05.045
- VernacularTitle:肝移植治疗慢加急性肝衰竭的临床研究进展
- Author:
Jiang LI
1
;
Xing DAI
2
;
Dazhi TIAN
1
;
Wentao JIANG
1
;
Zhongyang SHEN
1
Author Information
1. Department of Liver Transplantation, Tianjin First Central Hospital, Tianjin 300110, China
2. The First Central College of Tianjin Medical University, Tianjin 300110, China
- Publication Type:Reviews
- Keywords:
Acute-On-Chronic Liver Failure;
Liver Transplantation;
Liver, Artificial;
Multiple Organ Failure
- From:
Journal of Clinical Hepatology
2022;38(5):1188-1191
- CountryChina
- Language:Chinese
-
Abstract:
Acute-on-chronic liver failure (ACLF) is a disease of rapid deterioration of liver function caused by the acute exacerbation of chronic liver diseases, and it is often associated with multiple organ failure and has a poorer prognosis than common liver cirrhosis. Many studies suggest that timely liver transplantation can significantly improve the survival rate of patients with ACLF; however, there are currently no reliable guidelines that point out the indications for liver transplantation in patients with ACLF. This article summarizes recent studies and discusses the indication, timing, and prognosis of liver transplantation in ALCF patients.
