Production mechanism and detection value of anti-gp210 antibody in primary biliary cholangitis
10.3969/j.issn.1001-5256.2022.06.041
- VernacularTitle:抗gp210抗体在原发性胆汁性胆管炎中的产生机制与检测价值
- Author:
Jihong ZHANG
1
;
Suling LI
2
Author Information
1. The First Clinical Medical College of Henan University of Chinese Medicine, Zhengzhou 450000, China
2. Department of Hepatology and Spleen-Stomach, The First Affiliated Hospital of Henan University of Chinese Medicine, Zhengzhou 450000, China
- Publication Type:Reviews
- Keywords:
Liver Cirrhosis, Biliary;
Antibodies;
Diagnosis;
Prognosis
- From:
Journal of Clinical Hepatology
2022;38(6):1416-1419
- CountryChina
- Language:Chinese
-
Abstract:
Primary biliary cholangitis (PBC) is one of the autoimmune liver diseases, and most patients have no obvious clinical manifestations in the early stage and have reached the advanced stage when symptoms appear. Therefore, it is necessary to make a confirmed diagnosis and evaluate prognosis as early as possible. Anti-gp210 antibody is of great value in the diagnosis of PBC and the prediction of disease progression, and the detection of anti-gp210 antibody can help to optimize the PBC scoring system. This article reviews the production mechanism and detection value of anti-gp210 antibody in PBC.