Correlation between Executive Function and Activities of Daily Living for Patients with Periventricular White Matter Lesions
10.3969/j.issn.1006-9771.2018.10.012
- VernacularTitle:脑室周围白质损伤患者执行功能损害与日常生活活动能力的相关性
- Author:
Jinfang WANG
1
,
2
;
Wanming WANG
2
;
Hongyan CHEN
3
;
Na YE
1
;
Yanling MA
1
;
Yumei ZHANG
1
Author Information
1. Department of Neurology, Beijing Tiantan Hospital, Capital Medical University, China National Clinical Research Center for Neurological Diseases, Center of Stroke, Beijing Institute for Brain Disorders, Beijing Key Laboratory of Translational Medicine for Cerebrovascular Disease, Beijing 100050, China;
2. Department of Neurology, General Hospital of The Yangtze River Shipping, Wuhan Brain Hospital, Wuhan, Hubei 453100, China;
3. Department of Neuroimaging, Beijing Tiantan Hospital, Capital Medical University, Beijing 100050, China
- Publication Type:Journal Article
- Keywords:
periventricular white matter lesions, cognitive impairment, executive function, activities of daily living
- From:
Chinese Journal of Rehabilitation Theory and Practice
2018;24(10):1182-1186
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the relationship between executive function and activities of daily living for patients with periventricular white matter lesions (PWMLs). Methods From January, 2016 to January, 2017, 35 PWMLs patients and 35 normal controls were collected. Their executive function and activities of daily living were assessed with neuropsychological tests and Activities of Daily Living Scale (ADL).Results Compared with the normal control group, the scores of Mini-Mental State Exam (MMSE) and Montreal Cognitive Assessment (MoCA) significantly decreased (t>13.726, P<0.001), the times of Trail-Making Test and Stroop Colour Word Test significantly lengthened, the Verbal Fluency Test score decreased (t=6.891, P=0.013) and the Digit-Symbol Substitution Test score did not improve (t=3.372, P=0.072) in PWMLs group. The Z score of executive function was positively correlated with ADL score (r=0.438, P=0.008).Conclusion The executive function and activities of daily living are impaired in PWMLs patients, and their activities of daily living is related to the severity of the executive function impairment.
