Chemical constituents of petroleum ether extract from the stems and leaves of Humulus scandens

VernacularTitle:葎草茎叶石油醚部位化学成分
Author: Biao SUN ¹ ; Yunlin AO ; Dezhi WANG ; Junya WANG ; Wencai YE ; Xiaoqi ZHANG
Author Information

1. 暨南大学药学院中药及天然药物研究所
Publication Type:Journal Article
Keywords: Moraceae; Humulus scandens; chemical constitutents; flavones
From: Journal of China Pharmaceutical University 2022;53(2):178-184
CountryChina
Language:Chinese
Abstract: To study the chemical constituents of petroleum ether extract from the stems and leaves of Humulus scandens (family of Moraceae), fifteen compounds were isolated from the stems and leaves of H.scandens by silica gel, Sephadex LH-20, ODS, and preparative HPLC chromatography.The structures were identified by physicochemical data and spectroscopic method as tectochrysin (1), chrysin (2), 5-hydroxy-3, 4'', 6, 7-tetramethoxyflavone (3), (2S)-5-hydroxy-7, 8-dimethoxyflavanone (4), imperatorin (5), phellopterin (6), ethyl 4-hydroxy-3-(3''-methyl-2''-butenyl)benzoate (7), p-hydroxy-phenylpropionic acid (8), ethyl p-hydroxycinnamate (9), p-hydroxybenzaldehyde (10), anofinic acid (11), 5,6-dehydrokavain (12), physcion (13), olean-12-ene-3,?11-dione (14) and ergosta-4, 6, 8 (14), 22-tetraen-3-one (15), respectively.All compounds were isolated from this plant for the first time.