Refinement review of the interactions between triazole antifungal agents and statins based on the optimization of the pre-prescription audit system
10.12206/j.issn.1006-0111.202109126
- VernacularTitle:基于前置审核系统优化的三唑类抗真菌药与他汀类药物相互作用精细化审核
- Author:
Sheng LIU
1
;
Min CHEN
1
;
Yuanzhen TU
1
Author Information
1. Department of Pharmacy, Mianyang Central Hospital, School of Medicine, University of Electronic Science and Technology of Chinese, Mianyang 621000, China.
- Keywords:
pre-prescription review system;
triazole antifungal agents;
statins;
interactions;
refined review
- From:
Journal of Pharmaceutical Practice
2022;40(2):175-179
- CountryChina
- Language:Chinese
-
Abstract:
Objective To better carries out the review of the interaction between triazole antifungal drugs and statins, ensure drug safety for patients and improve the efficiency of the manual review of pharmacists. Methods The advantageous combination with less interaction between the two kinds of drug was obtained by summarizing the interaction information of triazole antifungal drugs and statins. At the same time, optimizing the process of full manual reviews for drug interaction, and the advantageous combination of the two kinds of drug will be set up in advance on the doctor side of the review system. Doctors can adjust the drug in time according to the prompts of the information system when there is a significant interaction of the two kinds of drug in the prescription or medical order, which is issued by the doctors. Results After optimization, most doctors choose the drug combination of less interaction between the two kinds of drug according to the system prompts. The number of drug combinations of significant interaction which is manually reviewed by pharmacists is significantly reduced (P<0.05), and the review efficiency is improved, the drug safety risks brought by drug interactions to patients are reduced. Conclusion Refinement review of drug interactions between triazole antifungal agents and statins based on the optimization of the pre-audit system plays a positive role in improving the safety of patients’ medication and the efficiency of pharmacists' manual auditing.
