A Case of Thyrotoxic Periodic Paralysis in Adolescent with Graves' Disease.
10.6065/jkspe.2011.16.3.196
- Author:
Ki Won OH
1
;
Jin Young JEONG
;
Joon Sung KIM
Author Information
1. Department of Pediatrics, Ulsan University Hospital, University of Ulsan College of Medicine, Ulsan, Korea. pedkjs@uuh.ulsan.kr
- Publication Type:Case Report
- Keywords:
Hyperthyroidism;
Hypokalemic periodic paralysis;
Adolescent
- MeSH:
Adolescent;
Asian Continental Ancestry Group;
Child;
Exercise;
Follow-Up Studies;
Goiter;
Graves Disease;
Humans;
Hyperthyroidism;
Hypokalemia;
Hypokalemic Periodic Paralysis;
Leg;
Lower Extremity;
Male;
Muscle, Skeletal;
Paralysis;
Potassium;
Tachycardia, Sinus;
Thyroid Function Tests;
Thyroid Gland
- From:Journal of Korean Society of Pediatric Endocrinology
2011;16(3):196-200
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Thyrotoxic periodic paralysis (TPP) is a rare complication of hyperthyroidism characterized by recurrent paralysis of skeletal muscle and hypokalemia caused by a massive intracellular shift of potassium. TPP mainly affects young male patients of Asian descent. We describe a case of TPP in a 14-year-old girl who presented with palpitation and intermittent weakness of the lower extremities especially after physical exercises. The patient showed sinus tachycardia, proximal weakness of both legs and a severe hypokalemia. Thyroid function tests showed hyperthyroidism, and thyroid scan revealed diffusely enlarged goiter consistent with Graves' disease. After the management with antithyroid drug, beta-adrenergic blocker and potassium supplementation for TPP, she has remained euthyroid state and symptom free on the follow-up. TPP should be considered in children with acute paralysis of skeletal muscle and hypokalemia, also thyroid function should be evaluated.
