Research progress of change of platelet in blood stasis syndrome and effect of traditional Chinese medicine.
10.19540/j.cnki.cjcmm.20210629.701
- Author:
Zi-Yan WANG
1
;
Lei LI
1
;
Jian-Xun LIU
1
;
Hong-Xu MENG
1
;
Lan MIAO
1
;
Ming-Qian SUN
1
;
Ye-Hao ZHANG
1
Author Information
1. Beijing Key Laboratory of Chinese Materia Pharmacology, National Cardiouascular Disease Research Center of Tradtional Chinese Medicine, Institute of Basic Medical Sciences of Xiyuan hospital,China Academy of Chinese Medical Sciences Beijing 100091, China.
- Publication Type:Journal Article
- Keywords:
activating blood and resolving stasis;
monomers of Chinese medicine;
platelet;
platelet activation abnormality;
systems biology;
traditional Chinese medicine syndrome of blood stasis
- MeSH:
Blood Platelets;
Coronary Disease;
Humans;
Medicine, Chinese Traditional;
Platelet Activation;
Syndrome
- From:
China Journal of Chinese Materia Medica
2021;46(20):5201-5209
- CountryChina
- Language:Chinese
-
Abstract:
The traditional Chinese medicine(TCM) syndrome of blood stasis refers to blood stagnation in meridians and viscera, with the main symptoms of pain, mass, bleeding, purple tongue, and unsmooth pulse. Cardiovascular and cerebrovascular diseases are among the major chronic diseases seriously harming the health of the Chinese. Among the coronary heart disease and stroke patients, most demonstrate the blood stasis syndrome. Platelet is considered to be one of the necessary factors in thrombosis, which closely relates to the TCM syndrome of blood stasis and the occurrence of cardiovascular and cerebrovascular diseases. The clinical and laboratory research on platelet activation and aggregation has been paid more and more attention. Its purpose is to treat and prevent blood stasis syndrome. In this study, the authors analyzed the research on the dysfunctions of platelets in blood stasis syndrome, biological basis of TCM blood stasis syndrome, and the effect of blood-activating stasis-resolving prescriptions on platelets, aiming at providing a reference for exploring the mechanism of platelet intervention in the treatment of TCM blood stasis syndrome and the pathways and targets of Chinese medicine in the prevention and treatment of the syndrome.
