Effect of micro/nanoscaled Ti phosphate/Ti oxide hybrid coating on the osseointegration of Ti implants.
- Author:
Jie ZHANG
1
;
Song-Song ZHU
1
;
Nan JIANG
1
Author Information
- Publication Type:Journal Article
- Keywords: Ti oxide; Ti phosphate; hierarchical structure; micro/nanoscale morphology; osseointegration
- MeSH: Animals; Dental Implants; Osseointegration; Osteogenesis; Oxides; Phosphates; Rats; Surface Properties; Titanium
- From: West China Journal of Stomatology 2021;39(5):531-539
- CountryChina
- Language:English
-
Abstract:
OBJECTIVES:This study was performed to fabricate a bionic coating with titanium (Ti) phosphate to promote the osseointegration of Ti substrate implants.
METHODS:Phosphorylated micro/nanocoating was prepared on the surface of pure titanium (i.e., TiP-Ti) by hydrothermal process under special pressure, and the untreated smooth pure titanium (cp-Ti) was selected as the control. To evaluate the characteristics of the coating surface, scanning electron microscopy, X-ray diffraction, atomic force microscopy, and contact-angle measurement were performed. In addition, the effects of TiP-Ti on the proliferation, adhesion, and differentiation of rat bone marrow mesenchymal stem cells (BMSCs) were investigated by using
RESULTS:The TiP-Ti surface presented a bionic structure with coexisting nanoscale 3D spatial structure and microscale pores.
CONCLUSIONS:A bionic structure with TiP-Ti micro/nanoscale coating was successfully fabricated, indicating a promising method for modifying the surface of implants.
