Extraskeletal Calcifications in Children with Maintenance Peritoneal Dialysis
10.3339/jkspn.2021.25.2.117
- Author:
Eunhye OH
1
;
Jeesu MIN
;
Seon Hee LIM
;
Ji Hyun KIM
;
Il-Soo HA
;
Hee Gyung KANG
;
Yo Han AHN
Author Information
1. Department of Pediatrics, Seoul National University Children's Hospital, Seoul, Republic of Korea
- Publication Type:3
- From:Childhood Kidney Diseases
2021;25(2):117-121
- CountryRepublic of Korea
- Language:English
-
Abstract:
Chronic kidney disease (CKD)-mineral and bone disorder (CKD-MBD) is a common complication of CKD, often accompanied by extra-skeletal calcification in adult patients. As increased vascular calcification is predicted to increase cardiovascular mortality and morbidity, the revised Kidney Disease: Improving Global Outcomes guidelines recommend avoiding calcium-containing phosphate chelators. However, extra-skeletal calcification is less commonly noticed in pediatric patients. Here, we report our experience of such a complication in pediatric patients receiving maintenance peritoneal dialysis. Extra-skeletal calcification was noticed at the corneas, pelvic cavity, and soft tissues of the lower leg in 4 out of 32 patients on maintenance peritoneal dialysis. These patients experienced the aggravation of extra-skeletal calcifications during peritoneal dialysis, and 2 of them underwent excisional operations. It is required to monitor extra-skeletal calcifications in children on kidney replacement therapy.
