Progress of clinicopathological features, diagnosis and treatment and screening of early-onset colorectal cancer
10.3760/cma.j.cn115355-20210822-00364
- VernacularTitle:早发性结直肠癌临床病理特征、诊治及筛查研究进展
- Author:
Lingling WANG
1
;
Ming YANG
;
Haipeng CHEN
;
Zheng LIU
;
Xishan WANG
Author Information
1. 国家癌症中心 国家肿瘤临床医学研究中心 中国医学科学院北京协和医学院肿瘤医院结直肠外科，北京 100021
- Keywords:
Colorectal neoplasms;
Genetic testing;
Pathology, molecular;
Prognosis
- From:
Cancer Research and Clinic
2021;33(11):801-804
- CountryChina
- Language:Chinese
-
Abstract:
The incidence of early-onset colorectal cancer is increasing year by year, and it occupies an important position in colorectal cancer. Most of the characteristics of patients with early-onset colorectal cancer are different from those with late-onset colorectal cancer, the patients are diagnosed in a late stage, and their pathological manifestations show a type of poor prognosis. At present, there is a lack of consensus and guideline for the diagnosis, treatment and screening of early-onset colorectal cancer. A full understanding of the characteristics of early-onset colorectal cancer helps to understand its pathogenesis and guide screening and treatment to reduce the incidence and mortality of colorectal cancer. This article reviews the clinicopathological characteristics, molecular pathological mechanisms, diagnosis and treatment, and prognosis of early-onset colorectal cancer, in order to provide references for elucidating its etiology and formulating scientific and standardized screening strategies.
