Clinical promotion and application of liquid chromatography-tandem mass spectrometry face challenges
10.3760/cma.j.cn114452-20210618-00382
- VernacularTitle:液相色谱-串联质谱临床推广与应用面临挑战
- Author:
Xianzhang HUANG
1
Author Information
1. 广东省中医院(广州中医药大学第二附属医院)检验医学部,广州510120
- Keywords:
Liquid chromatography tandem mass spectrometry;
Omics;
Quantitative detection;
Clinical application
- From:
Chinese Journal of Laboratory Medicine
2021;44(8):661-663
- CountryChina
- Language:Chinese
-
Abstract:
Liquid chromatography tandem mass spectrometry (LC-MS/MS) is rapidly applied and developed in the field of laboratory medicine. High resolution mass spectrometry promotes efficient screening of biomarkers. Triple quadrupole mass spectrometry helps verify the diagnosis of disease and monitoring efficacy of biomarkers. Its application runs through different fields and links from omics research to experimental diagnosis, and has gradually become an indispensable technical means of disease research and diagnosis. At present, most LC-MS platforms are in the stage of medical research, and there are still some challenges in clinical promotion and application.