Research progress of optical coherence tomography and optical coherence tomography angiography in Leber hereditary optic neuropathy

VernacularTitle:光相干断层扫描及其血管成像在Leber遗传性视神经病变中的应用研究进展
Author: Yufang CHENG ¹ ; Changzheng CHEN
Author Information

1. 武汉大学人民医院眼科中心　430060
Keywords: Optic atrophy, hereditary, Leber; Tomography, optical coherence; Review
From: Chinese Journal of Ocular Fundus Diseases 2021;37(10):821-825
CountryChina
Language:Chinese
Abstract: Leber hereditary optic neuropathy (LHON) is a maternally inherited mitochondrial disease. It is clinically recognizable by painless, bilateral loss of vision, and the prognosis of vision is generally poor. In recent years, the information provided by optical coherence tomography (OCT) and OCT angiography (OCTA) has greatly improved people's understanding of LHON, and new progress has been made in the intervention and treatment of LHON. A detailed understanding of the structural changes of retina and choroid under OCT and OCTA of the natural course and after treatment of LHON, may provide reference for revealing the pathogenesis, prediction of onset time, differential diagnosis, follow-up of treatment effect and prognosis of LHON.