Mid-term clinical outcome analysis of aortic valve repair for rheumatic aortic valve disease
	    		
		   		
		   			
		   		
	    	
    	 
    	10.3760/cma.j.cn112434-20210330-00118
   		
        
        	
        		- VernacularTitle:主动脉瓣修复术治疗风湿性主动脉瓣病变的术后中期疗效评估
 
        	
        	
        	
        		- Author:
	        		
		        		
		        		
			        		Yan LI
			        		
			        		
			        		
			        			1
			        			
			        		
			        		
			        		
			        		
			        		;
		        		
		        		
		        		
			        		Jintao FU
			        		
			        		;
		        		
		        		
		        		
			        		Yuqing JIAO
			        		
			        		;
		        		
		        		
		        		
			        		Yixin JIA
			        		
			        		;
		        		
		        		
		        		
			        		Chunlei XU
			        		
			        		;
		        		
		        		
		        		
			        		Hong CHEN
			        		
			        		;
		        		
		        		
		        		
			        		Qiuming HU
			        		
			        		;
		        		
		        		
		        		
			        		Zonghao CHEN
			        		
			        		;
		        		
		        		
		        		
			        		Wei HAN
			        		
			        		;
		        		
		        		
		        		
			        		Xu MENG
			        		
			        		
		        		
		        		
		        		
		        		
		        			
			        		
			        		Author Information
			        		
		        		
		        		
			        		
			        		
			        			1. 首都医科大学附属北京安贞医院心脏外科中心 100029
			        		
		        		
	        		
        		 
        	
        	
        	
        	
        		- Keywords:
        			
	        			
	        				
	        				
			        		
				        		Rheumatic heart disease;
			        		
			        		
			        		
				        		Aortic valve repair;
			        		
			        		
			        		
				        		Outcome anaylsis
			        		
			        		
	        			
        			
        		
 
        	
            
            
            	- From:
	            		
	            			Chinese Journal of Thoracic and Cardiovascular Surgery
	            		
	            		 2021;37(8):467-471
	            	
            	
 
            
            
            	- CountryChina
 
            
            
            	- Language:Chinese
 
            
            
            	- 
		        	Abstract:
			       	
			       		
				        
				        	Objective:To evaluate the mid-term outcomes of patients with rheumatic heart disease who underwent aortic valve repair surgery in a prospective cohort.Methods:From January 2016 to December 2020, a total of 54 patients with rheumatic heart disease underwent aortic valve repair surgery in Beijing Anzhen Hospital, with an average age of (50.61±13.29) years, including 29 females (53.7%). There were 31 patients (57.4%) had pure aortic insufficiency, 2 patients (3.7%) had pure aortic stenosis and 21 patients (38.9%) had mixed lesion. During the same period, 43 patients (80.0%) underwent mitral valve surgery, 36 patients (66.7%) underwent tricuspid valve surgery, and 20 patients (37.0%) underwent atrial fibrillation radiofrequency ablation.The follow-up period was from 1 month to 61 months (median follow-up was 25 months). Paired rank-sum test was used to compare the differences in continuous variables among subjects, and Kaplan- Meier method was used to analyze the clinical outcomes during the follow-up period. Results:Proportion of moderate and severe aortic regurgitation Preoperatively was higher than that of discharge data, aortic valve orifice maximum velocity and left ventricular end-diastolic diameter were significantly lower than discharge data (all P<0.05). The 5-year survival rate was (96.1±2.7)% (2 patients died). The 5-year freedom from reoperation after aortic valve repair was (89.5±4.5)%(5 patients underwent redo surgery). The 5-year freedom from valvular-related complications was (91.3±4.2)%(3 patients suffered from complications). Conclusion:Aortic valve repair surgery for rheumatic aortic valve disease is feasible and has excellent early and mid-term results, it can be a reliable treatment option.