Magnetically controlled capsule endoscopy for preliminary risk assessment of upper gastrointestinal bleeding in elderly patients taking enteric-coated aspirin
10.3760/cma.j.cn321463-20210401-00220
- VernacularTitle:磁控胶囊内镜对服用肠溶阿司匹林老年患者上消化道出血风险评估的价值探讨
- Author:
Yan WANG
1
;
Feng GAO
;
Xinjuan LIU
;
Xiaoyun ZHANG
;
Ning LI
;
Yingxin GAO
;
Jianyu HAO
Author Information
1. 首都医科大学附属北京朝阳医院消化内科 100020
- Keywords:
Aspirin;
Gastrointestinal hemorrhage;
Aged;
Risk assessment;
Capsule endoscopes
- From:
Chinese Journal of Digestive Endoscopy
2021;38(7):565-568
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To investigate the clinical application value of magnetically controlled capsule endoscopy (MCCE) for risk assessment of upper gastrointestinal bleeding in elderly patients taking enteric-coated aspirin.Methods:Clinical data of elderly patients taking enteric-coated aspirin and undergoing MCCE from January 2018 to December 2020 in Beijing Chaoyang and Beijing Anzhen Hospital, Capital Medical University were analyzed. Patients were divided into low-risk group (scores ≤ 3) and moderate/high risk group (scores >3) to study the risk assessment of upper gastrointestinal bleeding in elderly patients taking enteric-coated aspirin.Results:A total of 66 patients (aged 60-81 years, 45 males and 21 females) were enrolled and 17 patients developed bleeding. The indicators of low-risk ( n=51) and moderate/high risk groups ( n=15) were as follows: the incidences of upper gastrointestinal bleeding were 17.6% and 53.3%( P<0.001), gastric ulcer 5.9% and 26.7% ( P<0.001), median gastric Lanza score 2.0 and 2.0( P=0.621), duodenal ulcer 2.0% and 18.8% ( P<0.001), median duodenal mucosal injury score 1.0 and 1.0( P=0.936), respectively. Receiver operator characteristic curve showed that the area under the curve of risk assessment of upper gastrointestinal bleeding in elderly patients taking enteric-coated aspirin by MCCE was 0.855. Conclusion:Risk assessment of upper gastrointestinal bleeding in elderly patients taking enteric-coated aspirin can be used to predict the risk of upper gastrointestinal bleeding, but the scoring rules need to be further improved. Moderate and high-risk patients should undergo MCCE to monitor aspirin related upper gastrointestinal mucosal injury.
