Risk assessment calculator for neonatal early-onset sepsis
10.3760/cma.j.cn113903-20210117-00046
- VernacularTitle:新生儿早发型败血症风险计算器在新生儿早发型败血症风险评估中的作用
- Author:
Xiuli DU
1
;
Siyuan JIANG
;
Yun CAO
Author Information
1. 国家儿童医学中心 复旦大学附属儿科医院新生儿科 国家卫生健康委员会新生儿疾病重点实验室（复旦大学），上海 201102
- Keywords:
Neonate sepsis;
Risk factors;
Anti-bacterial agents;
Risk assessment
- From:
Chinese Journal of Perinatal Medicine
2021;24(9):709-713
- CountryChina
- Language:Chinese
-
Abstract:
Early-onset sepsis (EOS) continues to be a significant cause of mortality and morbidity in neonates, with difficulty in early identification and a worse prognosis if the treatment is delayed. Clinically, a comprehensive evaluation is usually carried out according to high-risk factors in the perinatal period, early clinical manifestations after birth, and laboratory tests of patients. early empirical antibiotic treatment as soon as possible in suspected cases. However, there is an evidence gap for the standardized evaluation of the EOS risk factors and clinical manifestation, leading to unnecessary early antibiotic treatment in those neonates who are misdiagnosed with neonatal sepsis, resulting in adverse outcomes in the short and long term. Neonatal EOS risk calculator (NEOSC), a new quantitative algorithm for the evaluation of EOS risk in neonates in recent years, has been extensively reached in some developed countries and has been applied in clinical research, providing a new strategy to guide early antibiotic management in patients with suspected EOS. This review summarizes the research progress on NEOSC and its clinical application.
