Progress in clinical phenotype and pathogenesis of neuroimmunological diseases associtated with anti-glutamic acid decarboxylase antibody
10.3760/cma.j.cn113694-20210120-00057
- VernacularTitle:抗谷氨酸脱羧酶抗体相关神经免疫病的临床表型与研究进展
- Author:
Lin BAI
1
;
Haitao REN
;
Hongzhi GUAN
Author Information
1. 中国医学科学院北京协和医院神经科100730
- Keywords:
Glutamate decarboxylase;
Stiff-person syndrome;
Cerebellar ataxia;
Limbic encephalitis;
Epilepsy
- From:
Chinese Journal of Neurology
2021;54(9):963-967
- CountryChina
- Language:Chinese
-
Abstract:
Antibodies to glutamic acid decarboxylase (GAD) have been associated with several neurological syndromes, including stiff-person syndrome, cerebellar ataxia and epilepsy. This article critically reviews the main clinical characteristics and the evidence on the pathogenicity of GAD antibodies.