Phage therapy and its application and prospects in skin and genitourinary tract infections
- VernacularTitle:噬菌体疗法及其在皮肤和泌尿生殖道感染中的应用与展望
- Author:
Lili SHAO
1
;
Quanzhong LIU
Author Information
- Keywords: Infection; Bacteriophages; Drug resistance, microbial; Skin; Urinary tract infections; Reproductive tract infections; Therapy
- From: Chinese Journal of Dermatology 2021;54(10):924-927
- CountryChina
- Language:Chinese
- Abstract: The emergence of a large number of drug-resistant bacteria has brought severe challenges to clinical anti-infection treatment. Phage therapy is considered to be a very promising method to cope with this dilemma, which has been explored and applied in many disciplines. Its efficacy has also been confirmed in clearing skin and mucous membrane infections, and it has become a hot spot in international research. The use of phage cocktails, phage lysozymes and phage proteins has shown good efficacy in the treatment of drug-resistant Staphylococcus aureus, Pseudomonas aeruginosa, Escherichia coli, Klebsiella, Bacillus proteus, etc. This review summarizes the background, characteristics, development of phage therapy, and its application and prospects in skin and genitourinary tract infections.
