Depression as the first manifestation of primary hyperparathyroidism: A case report and literature review
	    		
		   		
		   			
		   		
	    	
    	 
    	10.3760/cma.j.cn311282-20201123-00779
   		
        
        	
        		- VernacularTitle:以抑郁症起病的原发性甲状旁腺功能亢进症一例报道并文献回顾
 
        	
        	
        	
        		- Author:
	        		
		        		
		        		
			        		Xiaoai YAO
			        		
			        		
			        		
			        			1
			        			
			        		
			        		
			        		
			        		
			        		;
		        		
		        		
		        		
			        		Xiuxia SONG
			        		
			        		;
		        		
		        		
		        		
			        		Lei XIU
			        		
			        		;
		        		
		        		
		        		
			        		Tao JIANG
			        		
			        		;
		        		
		        		
		        		
			        		Xiaomin WANG
			        		
			        		
		        		
		        		
		        		
		        		
		        			
			        		
			        		Author Information
			        		
		        		
		        		
			        		
			        		
			        			1. 首都医科大学附属北京世纪坛医院内分泌科,北京 100078
			        		
		        		
	        		
        		 
        	
        	
        	
        	
        		- Keywords:
        			
	        			
	        				
	        				
			        		
				        		Depression;
			        		
			        		
			        		
				        		Primary hyperparathyroidism;
			        		
			        		
			        		
				        		Patient health questionnaire -9
			        		
			        		
	        			
        			
        		
 
        	
            
            
            	- From:
	            		
	            			Chinese Journal of Endocrinology and Metabolism
	            		
	            		 2021;37(11):1009-1012
	            	
            	
 
            
            
            	- CountryChina
 
            
            
            	- Language:Chinese
 
            
            
            	- 
		        	Abstract:
			       	
			       		
				        
				        	We report a case of primary hyperparathyroidism(PHPT) with depressive symptoms as initial manifestation. Literature review was conduct to further analyze the etiology, clinical manifestations, diagnosis, treatment and prognosis of the disease. The initial symptoms of the patients was the mental system depression and kidney stones was found by physical examination. She first visited a doctor in the urology department after a kidney stones was found. Blood calcium 2.86 mmol/L was found. At second visit, a doctor from endocrinology department conducted a comprehensive examination on the patient′s coexisting mental and renal system symptoms, clearly identified, her as PHPT. The clinical manifestations of PHPT are diverse. Symptoms such as depression, anxiety, mood swings, etc. are rarely evaluated. PHPT patients with onset or accompanied by psychiatric symptoms should be paid attention to by doctors, Measures should be taken to improve the quality of life and prognosis of patients through early screening of blood calcium and parathyroid hormone for timely diagnosis.